HORDB

ID: hor002911
Uniprot ID: P38496
Protein name: Lom-AG-myotropin-1
Gene name: NA
Organism: Locusta migratoria (Migratory locust)
Family: NA
Source: animal
Expression: Male accessory glands.
Disease: NA
Comments: NA
Taxonomy: Locusta (genus), Oedipodinae (subfamily), Acrididae (family), Acridoidea (superfamily), Acridomorpha, Acrididea (infraorder), Caelifera (suborder), Orthoptera (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Function: This myotropic peptide is active on the oviduct and, to a lesser extent, on the hindgut. Transferred from the male to the female during copulation.
Mechanism: NA
Cross BBB: NO
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P20065-F1.pdb

hor002911_AF2.pdb

hor002911_ESM.pdb

Mass:	158179	Formula:	C62H98N18O17
Absent amino acids:	CDEHIMPQWY	Common amino acids:	AFG
pI:	11.65	Basic residues:	2
Polar residues:	5	Hydrophobic residues:	6
Hydrophobicity:	23.08	Boman Index:	-1266
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	67.69
Instability Index:	-886.15	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 2052501
Title: Lom-AG-myotropin: a novel myotropic peptide from the male accessory glands of Locusta migratoria.